Application of photocrosslinkable hyaluronan as a corneal perforation sealant


Conference Paper

A novel photocrosslinkable methacrylated hyaluronic acid has been synthesized for use as a corneal perforation sealant. The adhesion strength of this hydrogel to an epithelial surface was quantitated in vitro. In vivo application of this biopolymer sealed 95% of experimental corneal perforations allowing for complete stromal healing and the re-establishment of the cornea.

Duke Authors

Cited Authors

  • Grinstaff, MW; Miki, D; Pfister-Serres, A; Dastgheib, KA; Smeds, KA; Inoue, M; Hatchell, DL

Published Date

  • December 1, 1999

Published In

Volume / Issue

  • 2 /

Start / End Page

  • 717 -

International Standard Serial Number (ISSN)

  • 0589-1019

International Standard Book Number 10 (ISBN-10)

  • 0780356756

Citation Source

  • Scopus