Apical-basal polarity, Wnt signaling and vertebrate organogenesis.
Publication
, Journal Article
Karner, C; Wharton, KA; Carroll, TJ
Published in: Seminars in cell & developmental biology
April 2006
Wnt proteins elicit several distinct signal transduction cascades and regulate multiple cellular processes that have proven essential for embryonic development in all metazoans investigated. During embryonic development, epithelial cells become polarized along two axes: apical/basal and within the plane of the tissue. Growing evidence suggests that polarization along each axis is essential for normal embryonic development and that this polarization is regulated in part by the different branches of the Wnt pathway. Here, we review the role of A/B cell polarity in vertebrate organogenesis with a focus on the involvement of canonical Wnt signaling in this process.
Published In
Seminars in cell & developmental biology
DOI
EISSN
1096-3634
ISSN
1084-9521
Publication Date
April 2006
Volume
17
Issue
2
Start / End Page
214 / 222
Related Subject Headings
- Wnt Proteins
- Vertebrates
- Signal Transduction
- Organogenesis
- Epithelial Cells
- Developmental Biology
- Cell Polarity
- Animals
- 3101 Biochemistry and cell biology
- 1114 Paediatrics and Reproductive Medicine
Citation
APA
Chicago
ICMJE
MLA
NLM
Karner, C., Wharton, K. A., & Carroll, T. J. (2006). Apical-basal polarity, Wnt signaling and vertebrate organogenesis. Seminars in Cell & Developmental Biology, 17(2), 214–222. https://doi.org/10.1016/j.semcdb.2006.05.007
Karner, Courtney, Keith A. Wharton, and Thomas J. Carroll. “Apical-basal polarity, Wnt signaling and vertebrate organogenesis.” Seminars in Cell & Developmental Biology 17, no. 2 (April 2006): 214–22. https://doi.org/10.1016/j.semcdb.2006.05.007.
Karner C, Wharton KA, Carroll TJ. Apical-basal polarity, Wnt signaling and vertebrate organogenesis. Seminars in cell & developmental biology. 2006 Apr;17(2):214–22.
Karner, Courtney, et al. “Apical-basal polarity, Wnt signaling and vertebrate organogenesis.” Seminars in Cell & Developmental Biology, vol. 17, no. 2, Apr. 2006, pp. 214–22. Epmc, doi:10.1016/j.semcdb.2006.05.007.
Karner C, Wharton KA, Carroll TJ. Apical-basal polarity, Wnt signaling and vertebrate organogenesis. Seminars in cell & developmental biology. 2006 Apr;17(2):214–222.
Published In
Seminars in cell & developmental biology
DOI
EISSN
1096-3634
ISSN
1084-9521
Publication Date
April 2006
Volume
17
Issue
2
Start / End Page
214 / 222
Related Subject Headings
- Wnt Proteins
- Vertebrates
- Signal Transduction
- Organogenesis
- Epithelial Cells
- Developmental Biology
- Cell Polarity
- Animals
- 3101 Biochemistry and cell biology
- 1114 Paediatrics and Reproductive Medicine