A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer.
Publication
, Journal Article
Ferracci, F; Fassetta, G; Butler, MH; Floyd, S; Solimena, M; De Camilli, P
Published in: Neurology
September 11, 1999
A 72-year-old woman developed a lower motor neuron syndrome (MNS) 4 months before the appearance of breast cancer. Monoparesis progressed to quadriparesis despite high-dose IV immunoglobulins, plasma exchange, and azathioprine, and high-dose IV methylprednisolone. The patient improved only after the removal of the tumor. MRI demonstrated hyperintensities in the cervical spinal cord. The patient had antibodies that reacted with axonal initial segments and nodes of Ranvier. The findings suggest that in this patient lower MNS may be a paraneoplastic condition associated with breast cancer.
Duke Scholars
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
September 11, 1999
Volume
53
Issue
4
Start / End Page
852 / 855
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Motor Neuron Disease
- Magnetic Resonance Imaging
- Humans
- Fluorescent Antibody Technique
- Female
- Electromyography
- Breast Neoplasms
- Blotting, Western
- Autoantibodies
Citation
APA
Chicago
ICMJE
MLA
NLM
Ferracci, F., Fassetta, G., Butler, M. H., Floyd, S., Solimena, M., & De Camilli, P. (1999). A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer. Neurology, 53(4), 852–855. https://doi.org/10.1212/wnl.53.4.852
Ferracci, F., G. Fassetta, M. H. Butler, S. Floyd, M. Solimena, and P. De Camilli. “A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer.” Neurology 53, no. 4 (September 11, 1999): 852–55. https://doi.org/10.1212/wnl.53.4.852.
Ferracci F, Fassetta G, Butler MH, Floyd S, Solimena M, De Camilli P. A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer. Neurology. 1999 Sep 11;53(4):852–5.
Ferracci, F., et al. “A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer.” Neurology, vol. 53, no. 4, Sept. 1999, pp. 852–55. Pubmed, doi:10.1212/wnl.53.4.852.
Ferracci F, Fassetta G, Butler MH, Floyd S, Solimena M, De Camilli P. A novel antineuronal antibody in a motor neuron syndrome associated with breast cancer. Neurology. 1999 Sep 11;53(4):852–855.
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
September 11, 1999
Volume
53
Issue
4
Start / End Page
852 / 855
Location
United States
Related Subject Headings
- Neurology & Neurosurgery
- Motor Neuron Disease
- Magnetic Resonance Imaging
- Humans
- Fluorescent Antibody Technique
- Female
- Electromyography
- Breast Neoplasms
- Blotting, Western
- Autoantibodies