Central Nervous System Cancers, Version 1.2015.

Journal Article (Journal Article)

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS cancers. Primary and metastatic brain tumors are a heterogeneous group of neoplasms with varied outcomes and management strategies. These NCCN Guidelines Insights summarize the NCCN CNS Cancers Panel's discussion and highlight notable changes in the 2015 update. This article outlines the data and provides insight into panel decisions regarding adjuvant radiation and chemotherapy treatment options for high-risk newly diagnosed low-grade gliomas and glioblastomas. Additionally, it describes the panel's assessment of new data and the ongoing debate regarding the use of alternating electric field therapy for high-grade gliomas.

Full Text

Duke Authors

Cited Authors

  • Nabors, LB; Portnow, J; Ammirati, M; Baehring, J; Brem, H; Brown, P; Butowski, N; Chamberlain, MC; Fenstermaker, RA; Friedman, A; Gilbert, MR; Hattangadi-Gluth, J; Holdhoff, M; Junck, L; Kaley, T; Lawson, R; Loeffler, JS; Lovely, MP; Moots, PL; Mrugala, MM; Newton, HB; Parney, I; Raizer, JJ; Recht, L; Shonka, N; Shrieve, DC; Sills, AK; Swinnen, LJ; Tran, D; Tran, N; Vrionis, FD; Weiss, S; Wen, PY; McMillian, N; Engh, AM

Published Date

  • October 2015

Published In

Volume / Issue

  • 13 / 10

Start / End Page

  • 1191 - 1202

PubMed ID

  • 26483059

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2015.0148


  • eng

Conference Location

  • United States