Skip to main content
Journal cover image

Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry.

Publication ,  Journal Article
Acharya, KS; Keyhan, S; Acharya, CR; Yeh, JS; Provost, MP; Goldfarb, JM; Muasher, SJ
Published in: Fertil Steril
September 1, 2016

OBJECTIVE: To analyze donor oocyte cycles in the Society for Assisted Reproductive Technology (SART) registry to determine: 1) how many cycles complied with the 2009 American Society for Reproductive Medicine/SART embryo transfer guidelines; and 2) cycle outcomes according to the number of embryos transferred. For donor oocyte IVF with donor age <35 years, the consideration of single-embryo transfer was strongly recommended. DESIGN: Retrospective cohort study of United States national registry information. SETTING: Not applicable. PATIENT(S): A total of 13,393 donor-recipient cycles from 2011 to 2012. INTERVENTION(S): Embryos transferred in donor IVF cycles. MAIN OUTCOME MEASURE(S): Percentage of compliant cycles, multiple pregnancy rate. RESULT(S): There were 3,157 donor cleavage-stage transfers and 10,236 donor blastocyst transfers. In the cleavage-stage cycles, 88% met compliance criteria. The multiple pregnancy rate (MPR) was significantly higher in the noncompliant cycles. In a subanalysis of compliant cleavage-stage cycles, 91% transferred two embryos and only 9% single embryos. In those patients transferring two embryos, the MPR was significantly higher (33% vs. 1%). In blastocyst transfers, only 28% of the cycles met compliance criteria. The MPR was significantly higher in the noncompliant blastocyst cohort at 53% (compared with 2% in compliant cycles). CONCLUSION(S): The majority of donor cleavage-stage transfers are compliant with current guidelines, but the transfer of two embryos results in a significantly higher MPR compared with single-embryo transfer. The majority of donor blastocyst cycles are noncompliant, which appears to be driving an unacceptably high MPR in these cycles.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Fertil Steril

DOI

EISSN

1556-5653

Publication Date

September 1, 2016

Volume

106

Issue

3

Start / End Page

603 / 607

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Treatment Outcome
  • Single Embryo Transfer
  • Retrospective Studies
  • Registries
  • Pregnancy, Multiple
  • Pregnancy Rate
  • Pregnancy
  • Practice Patterns, Physicians'
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Acharya, K. S., Keyhan, S., Acharya, C. R., Yeh, J. S., Provost, M. P., Goldfarb, J. M., & Muasher, S. J. (2016). Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry. Fertil Steril, 106(3), 603–607. https://doi.org/10.1016/j.fertnstert.2016.04.039
Acharya, Kelly S., Sanaz Keyhan, Chaitanya R. Acharya, Jason S. Yeh, Meredith P. Provost, James M. Goldfarb, and Suheil J. Muasher. “Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry.Fertil Steril 106, no. 3 (September 1, 2016): 603–7. https://doi.org/10.1016/j.fertnstert.2016.04.039.
Acharya KS, Keyhan S, Acharya CR, Yeh JS, Provost MP, Goldfarb JM, et al. Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry. Fertil Steril. 2016 Sep 1;106(3):603–7.
Acharya, Kelly S., et al. “Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry.Fertil Steril, vol. 106, no. 3, Sept. 2016, pp. 603–07. Pubmed, doi:10.1016/j.fertnstert.2016.04.039.
Acharya KS, Keyhan S, Acharya CR, Yeh JS, Provost MP, Goldfarb JM, Muasher SJ. Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry. Fertil Steril. 2016 Sep 1;106(3):603–607.
Journal cover image

Published In

Fertil Steril

DOI

EISSN

1556-5653

Publication Date

September 1, 2016

Volume

106

Issue

3

Start / End Page

603 / 607

Location

United States

Related Subject Headings

  • Young Adult
  • United States
  • Treatment Outcome
  • Single Embryo Transfer
  • Retrospective Studies
  • Registries
  • Pregnancy, Multiple
  • Pregnancy Rate
  • Pregnancy
  • Practice Patterns, Physicians'