Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir.
Publication
, Journal Article
Cooper, C; Naggie, S; Saag, M; Yang, JC; Stamm, LM; Dvory-Sobol, H; Han, L; Pang, PS; McHutchison, JG; Dieterich, D; Sulkowski, M
Published in: Clin Infect Dis
August 15, 2016
UNLABELLED: We assessed the efficacy and safety of ledipasvir/sofosbuvir plus ribavirin for 24 weeks in 9 human immunodeficiency virus/hepatitis C virus-coinfected patients who relapsed after receiving 12 weeks of treatment with ledipasvir/sofosbuvir. Eight of 9 (89%) achieved sustained virologic response 12 weeks after the end of treatment. One patient relapsed at posttreatment week 4. These results suggest an effective salvage therapy for patients for whom direct-acting antiviral treatment has failed. CLINICAL TRIALS REGISTRATION: NCT02073656.
Duke Scholars
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Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
August 15, 2016
Volume
63
Issue
4
Start / End Page
528 / 531
Location
United States
Related Subject Headings
- Treatment Failure
- Sofosbuvir
- Salvage Therapy
- Ribavirin
- Recurrence
- Middle Aged
- Microbiology
- Humans
- Hepatitis C, Chronic
- Hepacivirus
Citation
APA
Chicago
ICMJE
MLA
NLM
Cooper, C., Naggie, S., Saag, M., Yang, J. C., Stamm, L. M., Dvory-Sobol, H., … Sulkowski, M. (2016). Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir. Clin Infect Dis, 63(4), 528–531. https://doi.org/10.1093/cid/ciw349
Cooper, Curtis, Susanna Naggie, Michael Saag, Jenny C. Yang, Luisa M. Stamm, Hadas Dvory-Sobol, LingLing Han, et al. “Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir.” Clin Infect Dis 63, no. 4 (August 15, 2016): 528–31. https://doi.org/10.1093/cid/ciw349.
Cooper C, Naggie S, Saag M, Yang JC, Stamm LM, Dvory-Sobol H, et al. Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir. Clin Infect Dis. 2016 Aug 15;63(4):528–31.
Cooper, Curtis, et al. “Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir.” Clin Infect Dis, vol. 63, no. 4, Aug. 2016, pp. 528–31. Pubmed, doi:10.1093/cid/ciw349.
Cooper C, Naggie S, Saag M, Yang JC, Stamm LM, Dvory-Sobol H, Han L, Pang PS, McHutchison JG, Dieterich D, Sulkowski M. Successful Re-treatment of Hepatitis C Virus in Patients Coinfected With HIV Who Relapsed After 12 Weeks of Ledipasvir/Sofosbuvir. Clin Infect Dis. 2016 Aug 15;63(4):528–531.
Published In
Clin Infect Dis
DOI
EISSN
1537-6591
Publication Date
August 15, 2016
Volume
63
Issue
4
Start / End Page
528 / 531
Location
United States
Related Subject Headings
- Treatment Failure
- Sofosbuvir
- Salvage Therapy
- Ribavirin
- Recurrence
- Middle Aged
- Microbiology
- Humans
- Hepatitis C, Chronic
- Hepacivirus