Patient characteristics as predictors of clinical outcome of distraction in treatment of severe ankle osteoarthritis.

Journal Article (Journal Article)

Osteoarthritis (OA) is a slowly progressive joint disease. Joint distraction can be a treatment of choice in case of severe OA. Prediction of failure will facilitate implementation of joint distraction in clinical practice. Patients with severe ankle OA, who underwent joint distraction were included. Survival analysis was performed over 12 years (n = 25 after 12 years). Regression analyses were used to predict failures and clinical benefit at 2 years after joint distraction (n = 111). Survival analysis showed that 44% of the patients failed, 17% within 2 years and 37% within 5 years after joint distraction (n = 48 after 5 years). Survival analysis in subgroups showed that the percentage failure was only different in women (30% after 2 years) versus men (after 11 years still no 30% failure). In the multivariate analyses female gender was predictive for failure 2 years after joint distraction. Gender and functional disability at baseline predicted more pain. Functional disability and pain at baseline were associated with more functional disability. Joint distraction shows a long-term clinical beneficial outcome. However, failure rate is considerable over the years. Female patients have a higher chance of failure during follow-up. Unfortunately, not all potential predictors could be investigated and other clinically significant predictors were not found.

Full Text

Duke Authors

Cited Authors

  • Marijnissen, ACA; Hoekstra, MCL; Pré, BCD; van Roermund, PM; van Melkebeek, J; Amendola, A; Maathuis, P; Lafeber, FPJG; Welsing, PMJ

Published Date

  • January 2014

Published In

Volume / Issue

  • 32 / 1

Start / End Page

  • 96 - 101

PubMed ID

  • 23983196

Electronic International Standard Serial Number (EISSN)

  • 1554-527X

Digital Object Identifier (DOI)

  • 10.1002/jor.22475


  • eng

Conference Location

  • United States