Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia.
Publication
, Journal Article
Sayour, EJ; Mousallem, T; Van Mater, D; Wang, E; Martin, P; Buckley, RH; Barfield, RC
Published in: Pediatr Blood Cancer
October 2016
Patients with common variable immunodeficiency (CVID) have a higher incidence of autoimmune disease, which may mark the disease onset; however, anemia secondary to pure red cell aplasia is an uncommon presenting feature. Here, we describe a case of CVID-like humoral immune deficiency in a child who initially presented with red cell aplasia and ultimately developed progressive bone marrow failure. Although bone marrow transplantation (BMT) has been associated with high mortality in CVID, our patient was successfully treated with a matched sibling BMT and engrafted with >98% donor chimerism and the development of normal antibody titers to diphtheria and tetanus toxoids.
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Published In
Pediatr Blood Cancer
DOI
EISSN
1545-5017
Publication Date
October 2016
Volume
63
Issue
10
Start / End Page
1856 / 1859
Location
United States
Related Subject Headings
- Red-Cell Aplasia, Pure
- Oncology & Carcinogenesis
- Male
- Immunity, Humoral
- Humans
- Common Variable Immunodeficiency
- Child
- Bone Marrow Transplantation
- 3213 Paediatrics
- 3211 Oncology and carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Sayour, E. J., Mousallem, T., Van Mater, D., Wang, E., Martin, P., Buckley, R. H., & Barfield, R. C. (2016). Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia. Pediatr Blood Cancer, 63(10), 1856–1859. https://doi.org/10.1002/pbc.26092
Sayour, Elias J., Talal Mousallem, David Van Mater, Endi Wang, Paul Martin, Rebecca H. Buckley, and Raymond C. Barfield. “Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia.” Pediatr Blood Cancer 63, no. 10 (October 2016): 1856–59. https://doi.org/10.1002/pbc.26092.
Sayour EJ, Mousallem T, Van Mater D, Wang E, Martin P, Buckley RH, et al. Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia. Pediatr Blood Cancer. 2016 Oct;63(10):1856–9.
Sayour, Elias J., et al. “Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia.” Pediatr Blood Cancer, vol. 63, no. 10, Oct. 2016, pp. 1856–59. Pubmed, doi:10.1002/pbc.26092.
Sayour EJ, Mousallem T, Van Mater D, Wang E, Martin P, Buckley RH, Barfield RC. Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia. Pediatr Blood Cancer. 2016 Oct;63(10):1856–1859.
Published In
Pediatr Blood Cancer
DOI
EISSN
1545-5017
Publication Date
October 2016
Volume
63
Issue
10
Start / End Page
1856 / 1859
Location
United States
Related Subject Headings
- Red-Cell Aplasia, Pure
- Oncology & Carcinogenesis
- Male
- Immunity, Humoral
- Humans
- Common Variable Immunodeficiency
- Child
- Bone Marrow Transplantation
- 3213 Paediatrics
- 3211 Oncology and carcinogenesis