Distilling complexity to advance cardiac tissue engineering.

Journal Article (Review;Journal Article)

The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the functional aspects of a healthy heart and disease pathology as well as to design replacement muscle for clinical therapy. Parts of this promise have been realized; others have not. In a meeting of scientists in this field, five central challenges or "big questions" were articulated that, if addressed, could substantially advance the current state of the art in modeling heart disease and realizing heart repair.

Full Text

Duke Authors

Cited Authors

  • Ogle, BM; Bursac, N; Domian, I; Huang, NF; Menasché, P; Murry, CE; Pruitt, B; Radisic, M; Wu, JC; Wu, SM; Zhang, J; Zimmermann, W-H; Vunjak-Novakovic, G

Published Date

  • June 2016

Published In

Volume / Issue

  • 8 / 342

Start / End Page

  • 342ps13 -

PubMed ID

  • 27280684

Pubmed Central ID

  • PMC4959426

Electronic International Standard Serial Number (EISSN)

  • 1946-6242

International Standard Serial Number (ISSN)

  • 1946-6234

Digital Object Identifier (DOI)

  • 10.1126/scitranslmed.aad2304


  • eng