Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group.

Journal Article (Journal Article)

Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease that is based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.

Full Text

Duke Authors

Cited Authors

  • Collins, SP; Levy, PD; Martindale, JL; Dunlap, ME; Storrow, AB; Pang, PS; Albert, NM; Felker, GM; Fermann, GJ; Fonarow, GC; Givertz, MM; Hollander, JE; Lanfear, DE; Lenihan, DJ; Lindenfeld, JM; Peacock, WF; Sawyer, DB; Teerlink, JR; Butler, J

Published Date

  • August 2016

Published In

Volume / Issue

  • 23 / 8

Start / End Page

  • 922 - 931

PubMed ID

  • 27286136

Electronic International Standard Serial Number (EISSN)

  • 1553-2712

Digital Object Identifier (DOI)

  • 10.1111/acem.13025


  • eng

Conference Location

  • United States