Combined Constant-Force and Constant-Velocity Single-Molecule Force Spectroscopy of the Conrotatory Ring Opening Reaction of Benzocyclobutene.

Journal Article

Single-molecule force spectroscopy (SMFS) of multi-mechanophore polymers has been used to provide kinetic and mechanistic insights into mechanochemical reactions. Whereas biological systems have benefitted from force clamp spectroscopy, synthetic polymers have been studied primarily with constant-velocity methods. Here, force clamp SMFS is applied to the mechanically accelerated conrotatory ring opening of benzocyclobutene, and a comparison with constant-velocity SMFS extends the range of available rate-versus-force data and corroborates the use of constant-velocity SMFS to extract force dependencies.

Full Text

Duke Authors

Cited Authors

  • Kouznetsova, TB; Wang, J; Craig, SL

Published Date

  • June 2017

Published In

Volume / Issue

  • 18 / 11

Start / End Page

  • 1486 - 1489

PubMed ID

  • 27348210

Electronic International Standard Serial Number (EISSN)

  • 1439-7641

International Standard Serial Number (ISSN)

  • 1439-4235

Digital Object Identifier (DOI)

  • 10.1002/cphc.201600463

Language

  • eng