Acute chiasmal abscess resulting from perineural extension of invasive sino-orbital aspergillosis in an immunocompetent patient.

Published

Journal Article

OBJECTIVE: Intracranially invasive sino-orbital aspergillosis is a rare entity seen predominantly in immunocompromised individuals. We report a unique case of an acute chiasmal abscess resulting from perineural extension of an indolent invasive sino-orbital aspergillosis in an immunocompetent patient. CASE DESCRIPTION: A 61-year-old healthy Ukrainian man presented with severe left retro-orbital pain and a gradual ipsilateral monocular vision loss with rapid progression to a contralateral temporal visual field cut. He was found to have an intracranially invasive sino-orbital Aspergillus fumigatus infection with perineural extension along the optic nerve complicated by an acute chiasmal abscess. RESULTS: The patient was managed with surgical debridement and adjuvant antifungal chemotherapy. The patient's life and vision were preserved. CONCLUSIONS: The case demonstrates that it is possible to successfully control advanced intracranial aspergillosis with tissue-sparing surgery and adjuvant antifungal chemotherapy in immunocompetent individuals.

Full Text

Duke Authors

Cited Authors

  • Leyngold, I; Olivi, A; Ishii, M; Blitz, A; Burger, P; Subramanian, PS; Gallia, G

Published Date

  • January 2014

Published In

Volume / Issue

  • 81 / 1

Start / End Page

  • 203.e1 - 203.e6

PubMed ID

  • 23973515

Pubmed Central ID

  • 23973515

Electronic International Standard Serial Number (EISSN)

  • 1878-8769

Digital Object Identifier (DOI)

  • 10.1016/j.wneu.2013.08.018

Language

  • eng

Conference Location

  • United States