The macroecology of infectious diseases: a new perspective on global-scale drivers of pathogen distributions and impacts.

Journal Article (Review;Journal Article)

Identifying drivers of infectious disease patterns and impacts at the broadest scales of organisation is one of the most crucial challenges for modern science, yet answers to many fundamental questions remain elusive. These include what factors commonly facilitate transmission of pathogens to novel host species, what drives variation in immune investment among host species, and more generally what drives global patterns of parasite diversity and distribution? Here we consider how the perspectives and tools of macroecology, a field that investigates patterns and processes at broad spatial, temporal and taxonomic scales, are expanding scientific understanding of global infectious disease ecology. In particular, emerging approaches are providing new insights about scaling properties across all living taxa, and new strategies for mapping pathogen biodiversity and infection risk. Ultimately, macroecology is establishing a framework to more accurately predict global patterns of infectious disease distribution and emergence.

Full Text

Duke Authors

Cited Authors

  • Stephens, PR; Altizer, S; Smith, KF; Alonso Aguirre, A; Brown, JH; Budischak, SA; Byers, JE; Dallas, TA; Jonathan Davies, T; Drake, JM; Ezenwa, VO; Farrell, MJ; Gittleman, JL; Han, BA; Huang, S; Hutchinson, RA; Johnson, P; Nunn, CL; Onstad, D; Park, A; Vazquez-Prokopec, GM; Schmidt, JP; Poulin, R

Published Date

  • September 2016

Published In

Volume / Issue

  • 19 / 9

Start / End Page

  • 1159 - 1171

PubMed ID

  • 27353433

Electronic International Standard Serial Number (EISSN)

  • 1461-0248

International Standard Serial Number (ISSN)

  • 1461-023X

Digital Object Identifier (DOI)

  • 10.1111/ele.12644


  • eng