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Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial.

Publication ,  Journal Article
Qureshi, NN; Hatcher, J; Chaturvedi, N; Jafar, TH; Hypertension Research Group,
Published in: BMJ (Clinical research ed.)
November 2007

To determine the impact of a simple educational package for general practitioners on adherence to antihypertensive drugs.Cluster randomised controlled trial.Six randomly selected communities in Karachi, Pakistan.200 patients with hypertension taking antihypertensive drugs; 78 general practitioners.Care by general practitioners specially trained in management of hypertension compared with usual care.Correct dosing, defined as percentage of prescribed doses taken, measured with electronic medication event monitoring system (MEMS) bottle.200 patients were enrolled, and 178 (89%) successfully completed six weeks of follow-up. Adherence was significantly greater in the special care group than in the usual care group (unadjusted mean percentage days with correct dose 48.1%, 95% confidence interval 35.8% to 60.4%, versus 32.4%, 22.6% to 42.3%; P=0.048). Adherence was also higher among patients who had higher levels of education (P<0.001), were encouraged by family members (P<0.001), believed in the effect of drugs (P<0.001), and had the purpose of the drugs explained to them (P<0.001).Special training of general practitioners in management of hypertension, emphasising good communication between doctors and patients, is more effective than usual care provided in the communities in Karachi. Such simple interventions should be adopted by other developing countries that are now facing an increasing burden of hypertension.Clinical trials NCT00330408 [ClinicalTrials.gov].

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Published In

BMJ (Clinical research ed.)

DOI

EISSN

1756-1833

ISSN

0959-8138

Publication Date

November 2007

Volume

335

Issue

7628

Start / End Page

1030

Related Subject Headings

  • Patient Compliance
  • Pakistan
  • Middle Aged
  • Hypertension
  • Humans
  • General & Internal Medicine
  • Family Practice
  • Education, Medical, Graduate
  • Cluster Analysis
  • Antihypertensive Agents
 

Citation

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ICMJE
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Qureshi, N. N., Hatcher, J., Chaturvedi, N., Jafar, T. H., & Hypertension Research Group, . (2007). Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. BMJ (Clinical Research Ed.), 335(7628), 1030. https://doi.org/10.1136/bmj.39360.617986.ae
Qureshi, Nudrat Noor, Juanita Hatcher, Nish Chaturvedi, Tazeen H. Jafar, and Tazeen H. Hypertension Research Group. “Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial.BMJ (Clinical Research Ed.) 335, no. 7628 (November 2007): 1030. https://doi.org/10.1136/bmj.39360.617986.ae.
Qureshi NN, Hatcher J, Chaturvedi N, Jafar TH, Hypertension Research Group. Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. BMJ (Clinical research ed). 2007 Nov;335(7628):1030.
Qureshi, Nudrat Noor, et al. “Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial.BMJ (Clinical Research Ed.), vol. 335, no. 7628, Nov. 2007, p. 1030. Epmc, doi:10.1136/bmj.39360.617986.ae.
Qureshi NN, Hatcher J, Chaturvedi N, Jafar TH, Hypertension Research Group. Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. BMJ (Clinical research ed). 2007 Nov;335(7628):1030.

Published In

BMJ (Clinical research ed.)

DOI

EISSN

1756-1833

ISSN

0959-8138

Publication Date

November 2007

Volume

335

Issue

7628

Start / End Page

1030

Related Subject Headings

  • Patient Compliance
  • Pakistan
  • Middle Aged
  • Hypertension
  • Humans
  • General & Internal Medicine
  • Family Practice
  • Education, Medical, Graduate
  • Cluster Analysis
  • Antihypertensive Agents