Pulmonary Hypertension in the Era of Mechanical Circulatory Support.

Journal Article (Journal Article;Review)

Left heart disease (LHD) represents the most common cause of pulmonary hypertension (PH), and is associated with worse prognosis compared with LHD without PH. In addition, PH due to LHD may prevent patients from receiving heart transplantation, because of risk of perioperative right ventricular failure. Current literature lacks comprehensive descriptions and management strategies of PH due to LHD. In this review, we summarize the literature that is available to highlight the definition, pathogenesis, and prognosis of PH due to LHD. Furthermore, we discuss the use of mechanical circulatory support (MCS) in this population. Finally, we provide recommendations regarding the management and reassessment of PH due to LHD in the specific context of MCS.

Full Text

Duke Authors

Cited Authors

  • Krishnamurthy, Y; Cooper, LB; Parikh, KS; Felker, GM; Milano, CA; Rogers, JG; Hernandez, AF; Patel, CB

Published Date

  • September 2016

Published In

Volume / Issue

  • 62 / 5

Start / End Page

  • 505 - 512

PubMed ID

  • 27442856

Pubmed Central ID

  • PMC5001897

Electronic International Standard Serial Number (EISSN)

  • 1538-943X

Digital Object Identifier (DOI)

  • 10.1097/MAT.0000000000000408


  • eng

Conference Location

  • United States