Physicians' perspectives regarding pragmatic clinical trials.

Published

Journal Article

AIM: Practicing physicians inevitably become involved in pragmatic clinical trials (PCTs), including comparative effectiveness research. We sought to identify physicians' perspectives related to PCTs. METHODS: In-depth semistructured interviews with 20 physicians in the USA. RESULTS: Although physicians are generally willing to participate in PCTs, their support is predicated on several factors including expected benefits, minimization of time and workflow burdens and physician engagement. Physicians communicated a desire to respect patients' rights and interests while maintaining a high level of care. CONCLUSION: Future work is needed to systematically assess the impact of PCTs on clinicians in meeting their ethical obligations to patients and the burdens clinicians are willing to accept in exchange for potential benefits.

Full Text

Duke Authors

Cited Authors

  • Topazian, R; Bollinger, J; Weinfurt, KP; Dvoskin, R; Mathews, D; Brelsford, K; DeCamp, M; Sugarman, J

Published Date

  • August 2016

Published In

Volume / Issue

  • 5 / 5

Start / End Page

  • 499 - 506

PubMed ID

  • 27417953

Pubmed Central ID

  • 27417953

Electronic International Standard Serial Number (EISSN)

  • 2042-6313

Digital Object Identifier (DOI)

  • 10.2217/cer-2016-0024

Language

  • eng

Conference Location

  • England