Impact of Retrograde Arch Extension in Acute Type B Aortic Dissection on Management and Outcomes.

Journal Article (Journal Article)

BACKGROUND: Optimal management of acute type B aortic dissection with retrograde arch extension is controversial. The effect of retrograde arch extension on operative and long-term mortality has not been studied and is not incorporated into clinical treatment pathways. METHODS: The International Registry of Acute Aortic Dissection was queried for all patients presenting with acute type B dissection and an identifiable primary intimal tear. Outcomes were stratified according to management for patients with and without retrograde arch extension. Kaplan-Meier survival curves were constructed. RESULTS: Between 1996 and 2014, 404 patients (mean age, 63.3 ± 13.9 years) were identified. Retrograde arch extension existed in 67 patients (16.5%). No difference in complicated presentation was noted (36.8% vs 31.7%, p = 0.46), as defined by limb or organ malperfusion, coma, rupture, and shock. Patients with or without retrograde arch extension received similar treatment, with medical management in 53.7% vs 56.5% (p = 0.68), endovascular treatment in 32.8% vs 31.1% (p = 0.78), open operation in 11.9% vs 9.5% (p = 0.54), or hybrid approach in 1.5% vs 3.0% (p = 0.70), respectively. The in-hospital mortality rate was similar for patients with (10.7%) and without (10.4%) retrograde arch extension (p = 0.96), and 5-year survival was also similar at 78.3% and 77.8%, respectively (p = 0.27). CONCLUSIONS: The incidence of retrograde arch dissection involves approximately 16% of patients with acute type B dissection. In the International Registry of Acute Aortic Dissection, this entity seems not to affect management strategy or early and late death.

Full Text

Duke Authors

Cited Authors

  • Nauta, FJH; Tolenaar, JL; Patel, HJ; Appoo, JJ; Tsai, TT; Desai, ND; Montgomery, DG; Mussa, FF; Upchurch, GR; Fattori, R; Hughes, GC; Nienaber, CA; Isselbacher, EM; Eagle, KA; Trimarchi, S; International Registry of Acute Aortic Dissection (IRAD) Investigators,

Published Date

  • December 2016

Published In

Volume / Issue

  • 102 / 6

Start / End Page

  • 2036 - 2043

PubMed ID

  • 27424469

Electronic International Standard Serial Number (EISSN)

  • 1552-6259

Digital Object Identifier (DOI)

  • 10.1016/j.athoracsur.2016.05.013


  • eng

Conference Location

  • Netherlands