Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development.

Journal Article (Journal Article;Review)

Preterm infants with retinopathy of prematurity are at increased risk of poor neurodevelopmental outcomes. Because the neurosensory retina is an extension of the central nervous system, anatomic abnormalities in the anterior visual pathway often relate to system and central nervous system health. We describe optical coherence tomography as a powerful imaging modality that has recently been adapted to the infant population and provides noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside. Optical coherence tomography has increased understanding of normal eye development and has identified several potential biomarkers of brain abnormalities and poorer neurodevelopment.

Full Text

Duke Authors

Cited Authors

  • Rothman, AL; Mangalesh, S; Chen, X; Toth, CA

Published Date

  • 2016

Published In

Volume / Issue

  • 8 /

Start / End Page

  • 123 - 133

PubMed ID

  • 28539807

Pubmed Central ID

  • PMC5398750

International Standard Serial Number (ISSN)

  • 1179-2744

Digital Object Identifier (DOI)

  • 10.2147/EB.S97660


  • eng

Conference Location

  • New Zealand