Dynamic Contrast-Enhanced MR Imaging in Head and Neck Cancer: Techniques and Clinical Applications.
In the past decade, dynamic contrast-enhanced MR imaging has had an increasing role in assessing the microvascular characteristics of various tumors, including head and neck cancer. Dynamic contrast-enhanced MR imaging allows noninvasive assessment of permeability and blood flow, both important features of tumor hypoxia, which is a marker for treatment resistance for head and neck cancer. Dynamic contrast-enhanced MR imaging has the potential to identify early locoregional recurrence, differentiate metastatic lymph nodes from normal nodes, and predict tumor response to treatment and treatment monitoring in patients with head and neck cancer. Quantitative analysis is in its early stage and standardization and refinement of technique are essential. In this article, we review the techniques of dynamic contrast-enhanced MR imaging data acquisition, analytic methods, current limitations, and clinical applications in head and neck cancer.
Duke Scholars
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Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Magnetic Resonance Imaging
- Image Interpretation, Computer-Assisted
- Humans
- Head and Neck Neoplasms
- Contrast Media
- 3406 Physical chemistry
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Magnetic Resonance Imaging
- Image Interpretation, Computer-Assisted
- Humans
- Head and Neck Neoplasms
- Contrast Media
- 3406 Physical chemistry
- 3209 Neurosciences
- 3202 Clinical sciences
- 1109 Neurosciences