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Refusal of Trabeculectomy for the Fellow Eye in Collaborative Initial Glaucoma Treatment Study (CIGTS) Participants.

Publication ,  Journal Article
Gupta, D; Musch, DC; Niziol, LM; Chen, PP
Published in: Am J Ophthalmol
June 2016

PURPOSE: To understand the reasons for refusal of fellow eye surgical treatment for glaucoma after first eye trabeculectomy. DESIGN: Post hoc analysis of data collected in a multicenter, randomized clinical trial. METHODS: Data from participants in the Collaborative Initial Glaucoma Treatment Study (CIGTS) who were randomized to and underwent initial trabeculectomy on their study eye, and whose fellow eye was eligible for surgical treatment, were analyzed. Participant demographic data and characteristics, surgical data from the study eye, and quality-of-life survey results were compared between groups that received or refused trabeculectomy in their fellow eye. The main outcome measure was patient refusal of fellow eye surgery for glaucoma. RESULTS: Of 159 participants who were randomized to and underwent trabeculectomy on their study eye and had a fellow eye that was eligible for surgery, 30 (19%) refused fellow eye surgery. Eligible patients who refused fellow eye trabeculectomy did not differ significantly in visual function or local eye symptoms from those that underwent fellow eye trabeculectomy (all P > .05). In a multivariable analysis of data, increased fellow eye preoperative intraocular pressure (IOP) was associated with decreased odds (OR = 0.89, P = .0188), study eye hypotony at 3 months postoperatively was associated with increased odds (OR = 7.24, P = .0125), and argon suture lysis procedure was associated with decreased odds (OR = 0.38, P = .0385) of surgery refusal. CONCLUSIONS: Refusal of fellow eye surgery was not uncommonly encountered in the CIGTS. Those who refused fellow eye surgery had lower fellow eye IOP and were more likely to have had hypotony after study eye trabeculectomy.

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Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

June 2016

Volume

166

Start / End Page

1 / 7

Location

United States

Related Subject Headings

  • Treatment Refusal
  • Trabeculectomy
  • Surveys and Questionnaires
  • Quality of Life
  • Postoperative Complications
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Intraocular Pressure
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gupta, D., Musch, D. C., Niziol, L. M., & Chen, P. P. (2016). Refusal of Trabeculectomy for the Fellow Eye in Collaborative Initial Glaucoma Treatment Study (CIGTS) Participants. Am J Ophthalmol, 166, 1–7. https://doi.org/10.1016/j.ajo.2016.03.016
Gupta, Divakar, David C. Musch, Leslie M. Niziol, and Philip P. Chen. “Refusal of Trabeculectomy for the Fellow Eye in Collaborative Initial Glaucoma Treatment Study (CIGTS) Participants.Am J Ophthalmol 166 (June 2016): 1–7. https://doi.org/10.1016/j.ajo.2016.03.016.
Gupta, Divakar, et al. “Refusal of Trabeculectomy for the Fellow Eye in Collaborative Initial Glaucoma Treatment Study (CIGTS) Participants.Am J Ophthalmol, vol. 166, June 2016, pp. 1–7. Pubmed, doi:10.1016/j.ajo.2016.03.016.
Journal cover image

Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

June 2016

Volume

166

Start / End Page

1 / 7

Location

United States

Related Subject Headings

  • Treatment Refusal
  • Trabeculectomy
  • Surveys and Questionnaires
  • Quality of Life
  • Postoperative Complications
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Intraocular Pressure
  • Humans