Contribution of cardiopulmonary exercise testing to the identification of latent systolic dysfunction in chronic aortic regurgitation.


Journal Article

Chronic aortic regurgitation (AR) is a valvulopathy of slow and insidious evolution, and patients may remain asymptomatic for a long period of time. Exercise-induced systolic dysfunction occurs during the natural history of chronic AR and is related to changes in both preload and afterload. We describe the case of a 58-year-old woman with a diagnosis of chronic AR who reported progressive dyspnea of six years' duration. A cardiopulmonary exercise test to assess functional capacity showed flattening of both oxygen uptake and oxygen pulse curves, suggesting latent systolic dysfunction related to chronic AR, which was later confirmed by stress Doppler echocardiogram with dynamic physical exercise.

Full Text

Cited Authors

  • De Santi, GL; de Carvalho, EEV; Costa, DC; Crescencio, JC; Dias Romano, MM; Schmidt, A; Simões, MV; Gallo, L

Published Date

  • May 7, 2013

Published In

Volume / Issue

  • 32 / 5

Start / End Page

  • 419 - 423

PubMed ID

  • 23663932

Pubmed Central ID

  • 23663932

Electronic International Standard Serial Number (EISSN)

  • 2174-2030

International Standard Serial Number (ISSN)

  • 0870-2551

Digital Object Identifier (DOI)

  • 10.1016/j.repc.2013.03.002


  • eng