Perspectives from NHLBI Global Health Think Tank Meeting for Late Stage (T4) Translation Research.


Journal Article (Review)

Almost three-quarters (74%) of all the noncommunicable disease burden is found within low- and middle-income countries. In September 2014, the National Heart, Lung, and Blood Institute held a Global Health Think Tank meeting to obtain expert advice and recommendations for addressing compelling scientific questions for late stage (T4) research-research that studies implementation strategies for proven effective interventions-to inform and guide the National Heart, Lung, and Blood Institute's global health research and training efforts. Major themes emerged in two broad categories: 1) developing research capacity; and 2) efficiently defining compelling scientific questions within the local context. Compelling scientific questions included how to deliver inexpensive, scalable, and sustainable interventions using alternative health delivery models that leverage existing human capital, technologies and therapeutics, and entrepreneurial strategies. These broad themes provide perspectives that inform an overarching strategy needed to reduce the heart, lung, blood, and sleep disorders disease burden and global health disparities.

Full Text

Duke Authors

Cited Authors

  • Engelgau, MM; Peprah, E; Sampson, UKA; Mishoe, H; Benjamin, IJ; Douglas, PS; Hochman, JS; Ridker, PM; Brandes, N; Checkley, W; El-Saharty, S; Ezzati, M; Hennis, A; Jiang, L; Krumholz, HM; Lamourelle, G; Makani, J; Narayan, KMV; Ohene-Frempong, K; Straus, SE; Stuckler, D; Chambers, DA; Belis, D; Bennett, GC; Boyington, JE; Creazzo, TL; de Jesus, JM; Krishnamurti, C; Lowden, MR; Punturieri, A; Shero, ST; Young, NS; Zou, S; Mensah, GA

Published Date

  • December 2017

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 341 - 348

PubMed ID

  • 27452772

Pubmed Central ID

  • 27452772

Electronic International Standard Serial Number (EISSN)

  • 2211-8179

Digital Object Identifier (DOI)

  • 10.1016/j.gheart.2016.03.640


  • eng

Conference Location

  • England