Unequal representation of genetic variation across ancestry groups creates healthcare inequality in the application of precision medicine.


Journal Article (Letter)

An important application of modern genomics is diagnosing genetic disorders. We use the largest publicly available exome sequence database to show that this key clinical service can currently be performed much more effectively in individuals of European genetic ancestry.

Full Text

Cited Authors

  • Petrovski, S; Goldstein, DB

Published Date

  • July 14, 2016

Published In

Volume / Issue

  • 17 / 1

Start / End Page

  • 157 -

PubMed ID

  • 27418169

Pubmed Central ID

  • 27418169

Electronic International Standard Serial Number (EISSN)

  • 1474-760X

International Standard Serial Number (ISSN)

  • 1465-6906

Digital Object Identifier (DOI)

  • 10.1186/s13059-016-1016-y


  • eng