Intestinal Failure: New Definition and Clinical Implications.

Journal Article (Journal Article;Review)

Intestinal failure (IF) is a state in which the nutritional demands of the body are not met by the gastrointestinal absorptive surface. It is a long-recognized complication associated with short bowel syndrome, which results in malabsorption after significant resection of the intestine for many reasons or functional dysmotility. Etiologies have included Crohn's disease, vascular complications, and the effects of radiation enteritis, as well as the effects of intestinal obstruction, dysmotility, or congenital defects. While IF has been long-recognized, it has historically not been uniformly defined, which has made both recognition and management challenging. This review examines the previous definitions of IF as well as the newer definition and classification of IF and how it is essential to IF clinical guidelines.

Full Text

Duke Authors

Cited Authors

  • Kappus, M; Diamond, S; Hurt, RT; Martindale, R

Published Date

  • September 2016

Published In

Volume / Issue

  • 18 / 9

Start / End Page

  • 48 -

PubMed ID

  • 27447791

Electronic International Standard Serial Number (EISSN)

  • 1534-312X

Digital Object Identifier (DOI)

  • 10.1007/s11894-016-0525-x


  • eng

Conference Location

  • United States