Effect of Comorbid Knee and Hip Osteoarthritis on Longitudinal Clinical and Health Care Use Outcomes in Older Adults With New Visits for Back Pain.

Journal Article (Journal Article)


To examine if a comorbid diagnosis of knee or hip osteoarthritis (OA) in older adults with new back pain visits is associated with long-term patient-reported outcomes and back-related health care use.


Prospective cohort study.


Three integrated health systems forming the Back pain Outcomes using Longitudinal Data cohort.


Participants (N=5155) were older adults (≥65y) with a new visit for back pain and a complete electronic health record data.


Not applicable; we obtained OA diagnoses using diagnostic codes in the electronic health record 12 months prior to the new back pain visit.

Main outcome measures

The Roland-Morris Disability Questionnaire (RDQ) and the EuroQol-5D (EQ-5D) were key patient-reported outcomes. Health care use, measured by relative-value units (RVUs), was summed for the 12 months after the initial visit. We used linear mixed-effects models to model patient-reported outcomes. We also used generalized linear models to test the association between comorbid knee or hip OA and total back-related RVUs.


Of the 5155 participants, 368 (7.1%) had a comorbid knee OA diagnosis, and 94 (1.8%) had a hip OA diagnosis. Of the participants, 4711 (91.4%) had neither knee nor hip OA. In adjusted models, the 12-month RDQ score was 1.23 points higher (95% confidence interval [CI], 0.72-1.74) for patients with knee OA and 1.26 points higher (95% CI, 0.24-2.27) for those with hip OA than those without knee or hip OA, respectively. A lower EQ-5D score was found among participants with knee OA (.02 lower; 95% CI, -.04 to -.01) and hip OA diagnoses (.03 lower; 95% CI, -.05 to -.01) compared with those without knee or hip OA, respectively. Comorbid knee or hip OA was not significantly associated with total 12-month back-related resource use.


Comorbid knee or hip OA in older adults with a new back pain visit was associated with modestly worse long-term disability and health-related quality of life.

Full Text

Duke Authors

Cited Authors

  • Rundell, SD; Goode, AP; Suri, P; Heagerty, PJ; Comstock, BA; Friedly, JL; Gold, LS; Bauer, Z; Avins, AL; Nedeljkovic, SS; Nerenz, DR; Kessler, L; Jarvik, JG

Published Date

  • January 2017

Published In

Volume / Issue

  • 98 / 1

Start / End Page

  • 43 - 50

PubMed ID

  • 27519927

Electronic International Standard Serial Number (EISSN)

  • 1532-821X

International Standard Serial Number (ISSN)

  • 0003-9993

Digital Object Identifier (DOI)

  • 10.1016/j.apmr.2016.06.022


  • eng