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Genetic Susceptibility to Fungal Infections: What is in the Genes?

Publication ,  Journal Article
Maskarinec, SA; Johnson, MD; Perfect, JR
Published in: Curr Clin Microbiol Rep
June 2016

The development of severe fungal infections has long been associated with traditional risk factors such as profound immunosuppression, yet it remains challenging to understand why under similar conditions only some patients will develop these infections while others will not. Recent studies have demonstrated the importance of host genetic variation in influencing the severity and susceptibility to invasive fungal infections (IFIs). In this review, we examine selected primary immunodeficiencies characterized by their vulnerability to a narrow range of fungal pathogens, and then focus on recently identified genetic polymorphisms associated with an increased susceptibility to IFIs.

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Published In

Curr Clin Microbiol Rep

DOI

ISSN

2196-5471

Publication Date

June 2016

Volume

3

Issue

2

Start / End Page

81 / 91

Location

Switzerland
 

Citation

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Chicago
ICMJE
MLA
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Maskarinec, S. A., Johnson, M. D., & Perfect, J. R. (2016). Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep, 3(2), 81–91. https://doi.org/10.1007/s40588-016-0037-3
Maskarinec, Stacey A., Melissa D. Johnson, and John R. Perfect. “Genetic Susceptibility to Fungal Infections: What is in the Genes?Curr Clin Microbiol Rep 3, no. 2 (June 2016): 81–91. https://doi.org/10.1007/s40588-016-0037-3.
Maskarinec SA, Johnson MD, Perfect JR. Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep. 2016 Jun;3(2):81–91.
Maskarinec, Stacey A., et al. “Genetic Susceptibility to Fungal Infections: What is in the Genes?Curr Clin Microbiol Rep, vol. 3, no. 2, June 2016, pp. 81–91. Pubmed, doi:10.1007/s40588-016-0037-3.
Maskarinec SA, Johnson MD, Perfect JR. Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep. 2016 Jun;3(2):81–91.
Journal cover image

Published In

Curr Clin Microbiol Rep

DOI

ISSN

2196-5471

Publication Date

June 2016

Volume

3

Issue

2

Start / End Page

81 / 91

Location

Switzerland