Using conjoint analysis to estimate healthy-year equivalents for acute conditions: an application to vasomotor symptoms.

Published

Journal Article

OBJECTIVE: Conventional standard gamble and time trade-off methods may be inappropriate for eliciting preferences for some health states because both require subjects to make trade-offs between a morbid health state and death. Thus, the objective of this study is to demonstrate the use of conjoint analysis to obtain time trade-off estimates of healthy-year equivalents (HYEs) for clinically relevant durations and severities of acute, self-limiting, or nonfatal conditions such as vasomotor symptoms. METHODS: A self-administered, web-enabled, graded-pairs conjoint-analysis survey was developed to elicit women's preferences for reducing the frequency and severity of vasomotor symptoms (daytime hot flushes and night sweats). Observed trade-offs between symptom duration and symptom relief were used to calculate HYEs for different severities and durations of vasomotor symptoms. RESULTS: A total of 523 women with a mean age of 52 years completed the survey. For these women, an improvement from severe to moderate vasomotor symptoms yields a gain of 4.44 HYEs, and an improvement from moderate to mild vasomotor symptoms over 1 year yields a gain of 4.62 HYEs over a period of 7 years. HYE gains for symptom relief are larger for younger women than for older women. CONCLUSIONS: Conjoint analysis is a feasible method for estimating HYEs for acute, self-limiting, or nonfatal conditions. This approach may provide an alternative utility-elicitation method when conventional standard gamble and time trade-off methods are inappropriate to the decision context.

Full Text

Duke Authors

Cited Authors

  • Johnson, FR; Hauber, AB; Ozdemir, S

Published Date

  • January 2009

Published In

Volume / Issue

  • 12 / 1

Start / End Page

  • 146 - 152

PubMed ID

  • 19911445

Pubmed Central ID

  • 19911445

Electronic International Standard Serial Number (EISSN)

  • 1524-4733

Digital Object Identifier (DOI)

  • 10.1111/j.1524-4733.2008.00391.x

Language

  • eng

Conference Location

  • United States