Research Reproducibility in Longitudinal Multi-Center Studies Using Data from Electronic Health Records.

Journal Article (Journal Article)

A fundamental premise of scientific research is that it should be reproducible. However, the specific requirements for reproducibility of research using electronic health record (EHR) data have not been sufficiently articulated. There is no guidance for researchers about how to assess a given project and identify provisions for reproducibility. We analyze three different clinical research initiatives that use EHR data in order to define a set of requirements to reproduce the research using the original or other datasets. We identify specific project features that drive these requirements. The resulting framework will support the much-needed discussion of strategies to ensure the reproducibility of research that uses data from EHRs.

Full Text

Duke Authors

Cited Authors

  • Zozus, MN; Richesson, RL; Walden, A; Tenenbaum, JD; Hammond, WE

Published Date

  • 2016

Published In

Volume / Issue

  • 2016 /

Start / End Page

  • 279 - 285

PubMed ID

  • 27570682

Pubmed Central ID

  • PMC5001777

International Standard Serial Number (ISSN)

  • 2153-4063


  • eng

Conference Location

  • United States