Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement.


Journal Article

Tuberculosis remains an important preventable disease in the United States. An effective strategy for reducing the transmission, morbidity, and mortality of active disease is the identification and treatment of latent tuberculosis infection (LTBI) to prevent progression to active disease.To issue a current US Preventive Services Task Force (USPSTF) recommendation on screening for LTBI.The USPSTF reviewed the evidence on screening for LTBI in asymptomatic adults seen in primary care, including evidence dating from the inception of searched databases.The USPSTF found adequate evidence that accurate screening tests for LTBI are available, treatment of LTBI provides a moderate health benefit in preventing progression to active disease, and the harms of screening and treatment are small. The USPSTF has moderate certainty that screening for LTBI in persons at increased risk for infection provides a moderate net benefit.The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation).

Full Text

Cited Authors

  • US Preventive Services Task Force, ; Bibbins-Domingo, K; Grossman, DC; Curry, SJ; Bauman, L; Davidson, KW; Epling, JW; García, FAR; Herzstein, J; Kemper, AR; Krist, AH; Kurth, AE; Landefeld, CS; Mangione, CM; Phillips, WR; Phipps, MG; Pignone, MP

Published Date

  • September 2016

Published In

Volume / Issue

  • 316 / 9

Start / End Page

  • 962 - 969

PubMed ID

  • 27599331

Pubmed Central ID

  • 27599331

Electronic International Standard Serial Number (EISSN)

  • 1538-3598

International Standard Serial Number (ISSN)

  • 0098-7484

Digital Object Identifier (DOI)

  • 10.1001/jama.2016.11046


  • eng