Spatially resolved reflectance spectroscopy of two-layer turbid media by densely packed multi-pixel photodiode reflectance probe

Conference Paper

Spatially-resolved diffuse reflectance (SRDR) measurements provide photon path information, and enable layered tissue analysis. This paper presents experimental SRDR measurements on two-layer PDMS skin tissue-mimicking phantoms of varying top layer thicknesses, and bulk phantoms of varying optical properties using concentric multi-pixel photodiode array (CMPA) probes, and corresponding forward Monte Carlo simulations. The CMPA is the most densely packed semiconductor SRDR probe reported to date. Signal contrasts between the single layer phantom and bi-layer phantoms with varying top layer thicknesses are as high as 80%. The mean error between the Monte Carlo simulations and the experiment is less than 6.2 %.

Full Text

Duke Authors

Cited Authors

  • Senlik, O; Greening, G; Muldoon, TJ; Jokerst, NM

Published Date

  • January 1, 2016

Published In

Volume / Issue

  • 9700 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781628419344

Digital Object Identifier (DOI)

  • 10.1117/12.2213124

Citation Source

  • Scopus