Local Recurrence and Ocular Adnexal Complications Following Electronic Surface Brachytherapy for Basal Cell Carcinoma of the Lower Eyelid.

Journal Article

Various treatment options exist for nonmelanoma skin cancer (NMSC), including topical agents, surgery, or definitive or adjuvant radiation therapy. Recently, electronic surface brachytherapy (ESB) has been described as a noninvasive option for NMSC. We report a case of local recurrence of basal cell carcinoma (BCC) and ocular complications following ESB to the lower eyelid.A man in his 60s presented with a recurrent BCC within the radiation field 10 months after undergoing ESB for a biopsy-proven BCC. In addition to the recurrence, he had contracture of the conjunctiva in the socket of his previously enucleated eye, as well as lower eyelid ectropion, resulting in displacement and loss of retention of his ocular prosthesis.Electronic surface brachytherapy should be used with caution, particularly in the periocular region because the late effects of hypofractionated radiation may cause ocular and orbital complications. To our knowledge, this is the first reported case of ocular complications with this modality. This case highlights a local recurrence following use of this new treatment modality, suggesting further investigation is warranted to determine the safety and efficacy of ESB.

Full Text

Duke Authors

Cited Authors

  • Eftekhari, K; Anderson, RL; Suneja, G; Bowen, A; Oberg, TJ; Bowen, GM

Published Date

  • September 2015

Published In

Volume / Issue

  • 151 / 9

Start / End Page

  • 1002 - 1004

PubMed ID

  • 26267892

Electronic International Standard Serial Number (EISSN)

  • 2168-6084

International Standard Serial Number (ISSN)

  • 2168-6068

Digital Object Identifier (DOI)

  • 10.1001/jamadermatol.2015.2613


  • eng