Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth.
Publication
, Journal Article
Zhou, Y; Yao, J; Wang, LV
Published in: Optics letters
July 2013
Due to strong light scattering in tissue, both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (OR-PAM) deteriorate sharply with depth. To reduce tissue scattering, we propose to use glycerol as an optical clearing agent in OR-PAM. Our results show that the imaging performance of OR-PAM can be greatly enhanced by optical clearing both in vitro and in vivo.
Duke Scholars
Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
July 2013
Volume
38
Issue
14
Start / End Page
2592 / 2595
Related Subject Headings
- Signal-To-Noise Ratio
- Photoacoustic Techniques
- Phantoms, Imaging
- Optics
- Optical Phenomena
- Microscopy
- Mice
- Image Processing, Computer-Assisted
- Epidermal Cells
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhou, Y., Yao, J., & Wang, L. V. (2013). Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth. Optics Letters, 38(14), 2592–2595. https://doi.org/10.1364/ol.38.002592
Zhou, Yong, Junjie Yao, and Lihong V. Wang. “Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth.” Optics Letters 38, no. 14 (July 2013): 2592–95. https://doi.org/10.1364/ol.38.002592.
Zhou Y, Yao J, Wang LV. Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth. Optics letters. 2013 Jul;38(14):2592–5.
Zhou, Yong, et al. “Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth.” Optics Letters, vol. 38, no. 14, July 2013, pp. 2592–95. Epmc, doi:10.1364/ol.38.002592.
Zhou Y, Yao J, Wang LV. Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth. Optics letters. 2013 Jul;38(14):2592–2595.
Published In
Optics letters
DOI
EISSN
1539-4794
ISSN
0146-9592
Publication Date
July 2013
Volume
38
Issue
14
Start / End Page
2592 / 2595
Related Subject Headings
- Signal-To-Noise Ratio
- Photoacoustic Techniques
- Phantoms, Imaging
- Optics
- Optical Phenomena
- Microscopy
- Mice
- Image Processing, Computer-Assisted
- Epidermal Cells
- Animals