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Photoacoustic tomography: fundamentals, advances and prospects.

Publication ,  Journal Article
Yao, J; Wang, LV
Published in: Contrast media & molecular imaging
September 2011

Optical microscopy has been contributing to the development of life science for more than three centuries. However, due to strong optical scattering in tissue, its in vivo imaging ability has been restricted to studies at superficial depths. Advances in photoacoustic tomography (PAT) now allow multiscale imaging at depths from sub-millimeter to several centimeters, with spatial resolutions from sub-micrometer to sub-millimeter. Because of this high scalability and its unique optical absorption contrast, PAT is capable of performing anatomical, functional, molecular and fluid-dynamic imaging at various system levels, and is playing an increasingly important role in fundamental biological research and clinical practice. This review discusses recent technical progress in PAT and presents corresponding applications. It ends with a discussion of several prospects and their technical challenges.

Duke Scholars

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Published In

Contrast media & molecular imaging

DOI

EISSN

1555-4317

ISSN

1555-4309

Publication Date

September 2011

Volume

6

Issue

5

Start / End Page

332 / 345

Related Subject Headings

  • Tomography
  • Photoacoustic Techniques
  • Nuclear Medicine & Medical Imaging
  • Microscopy, Acoustic
  • Humans
  • Animals
  • 4003 Biomedical engineering
  • 1004 Medical Biotechnology
  • 0903 Biomedical Engineering
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Yao, J., & Wang, L. V. (2011). Photoacoustic tomography: fundamentals, advances and prospects. Contrast Media & Molecular Imaging, 6(5), 332–345. https://doi.org/10.1002/cmmi.443
Yao, Junjie, and Lihong V. Wang. “Photoacoustic tomography: fundamentals, advances and prospects.Contrast Media & Molecular Imaging 6, no. 5 (September 2011): 332–45. https://doi.org/10.1002/cmmi.443.
Yao J, Wang LV. Photoacoustic tomography: fundamentals, advances and prospects. Contrast media & molecular imaging. 2011 Sep;6(5):332–45.
Yao, Junjie, and Lihong V. Wang. “Photoacoustic tomography: fundamentals, advances and prospects.Contrast Media & Molecular Imaging, vol. 6, no. 5, Sept. 2011, pp. 332–45. Epmc, doi:10.1002/cmmi.443.
Yao J, Wang LV. Photoacoustic tomography: fundamentals, advances and prospects. Contrast media & molecular imaging. 2011 Sep;6(5):332–345.
Journal cover image

Published In

Contrast media & molecular imaging

DOI

EISSN

1555-4317

ISSN

1555-4309

Publication Date

September 2011

Volume

6

Issue

5

Start / End Page

332 / 345

Related Subject Headings

  • Tomography
  • Photoacoustic Techniques
  • Nuclear Medicine & Medical Imaging
  • Microscopy, Acoustic
  • Humans
  • Animals
  • 4003 Biomedical engineering
  • 1004 Medical Biotechnology
  • 0903 Biomedical Engineering
  • 0304 Medicinal and Biomolecular Chemistry