Fast voice-coil scanning optical-resolution photoacoustic microscopy.

Journal Article (Journal Article)

We developed a photoacoustic imaging system that has real-time imaging capability with optical resolution. The imaging system is capable of scanning at 20 Hz over a 9 mm range and up to 40 Hz over a 1 mm scanning range. A focused laser beam provides a lateral resolution of 3.4 μm as measured in an optically nonscattering medium. Flows of micrometer-sized carbon particles or whole blood in a silicone tube and individual red blood cells (RBCs) in mouse ear capillaries were also imaged in real time, demonstrating the capability to image highly dynamic processes in vivo at a micrometer-scale resolution.

Full Text

Duke Authors

Cited Authors

  • Wang, L; Maslov, K; Yao, J; Rao, B; Wang, LV

Published Date

  • January 2011

Published In

Volume / Issue

  • 36 / 2

Start / End Page

  • 139 - 141

PubMed ID

  • 21263479

Pubmed Central ID

  • PMC3086411

Electronic International Standard Serial Number (EISSN)

  • 1539-4794

International Standard Serial Number (ISSN)

  • 0146-9592

Digital Object Identifier (DOI)

  • 10.1364/ol.36.000139

Language

  • eng