Photoacoustic elastography.
Journal Article (Journal Article)
Elastography can noninvasively map the elasticity distribution in biological tissue, which can potentially be used to reveal disease conditions. In this Letter, we have demonstrated photoacoustic elastography by using a linear-array photoacoustic computed tomography system. The feasibility of photoacoustic elastography was first demonstrated by imaging the strains of single-layer and bilayer gelatin phantoms with various stiffness values. The measured strains agreed well with theoretical values, with an average error of less than 5.2%. Next, in vivo photoacoustic elastography was demonstrated on a mouse leg, where the fat and muscle distribution was mapped based on the elasticity contrast. We confirmed the photoacoustic elastography results by ultrasound elastography performed simultaneously.
Full Text
Duke Authors
Cited Authors
- Hai, P; Yao, J; Li, G; Li, C; Wang, LV
Published Date
- February 2016
Published In
Volume / Issue
- 41 / 4
Start / End Page
- 725 - 728
PubMed ID
- 26872173
Pubmed Central ID
- PMC4858317
Electronic International Standard Serial Number (EISSN)
- 1539-4794
International Standard Serial Number (ISSN)
- 0146-9592
Digital Object Identifier (DOI)
- 10.1364/ol.41.000725
Language
- eng