Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi


Conference Paper

© 2015 SPIE. The addition of photoacoustic endoscopy to conventional endoscopic ultrasound offers imaging capabilities that may improve diagnosis and clinical care of gastrointestinal tract diseases. In this study, using a 3.8-mm diameter dual-mode photoacoustic and ultrasonic endoscopic probe, we investigated photoacoustic and ultrasonic image features of rabbit esophagi. Specifically, we performed ex vivo imaging of intact rabbit esophagi and correlated the acquired images with histology. Without motion artifact-based limitations, we were able to utilize the full resolving power of the endoscopic device and acquire the first three-dimensional vasculature map of the esophagus and mediastinum, along with coregistered tissue density information. Here, we present the experimental results and discuss potential clinical applications of the technique.

Full Text

Duke Authors

Cited Authors

  • Yang, JM; Favazza, C; Yao, J; Chen, R; Zhou, Q; Shung, KK; Wang, LV

Published Date

  • January 1, 2015

Published In

Volume / Issue

  • 9323 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781628414134

Digital Object Identifier (DOI)

  • 10.1117/12.2080294

Citation Source

  • Scopus