In vivo optically encoded photoacoustic flowgraphy.

Journal Article (Journal Article)

We present an optically encoded photoacoustic (PA) flow imaging method based on optical-resolution PA microscopy. An intensity-modulated continuous-wave laser photothermally encodes the flowing medium, and a pulsed laser generates PA waves to image the encoded heat pattern. Flow speeds can be calculated by cross correlation. The method was validated in phantoms at flow speeds ranging from 0.23 to 11  mm/s. Venous blood flow speed in a mouse ear was also measured.

Full Text

Duke Authors

Cited Authors

  • Zhang, R; Wang, L; Yao, J; Yeh, C-H; Wang, LV

Published Date

  • July 2014

Published In

Volume / Issue

  • 39 / 13

Start / End Page

  • 3814 - 3817

PubMed ID

  • 24978744

Pubmed Central ID

  • PMC4165860

Electronic International Standard Serial Number (EISSN)

  • 1539-4794

International Standard Serial Number (ISSN)

  • 0146-9592

Digital Object Identifier (DOI)

  • 10.1364/ol.39.003814


  • eng