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Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration

Publication ,  Conference
Zhou, Y; Yao, J; Maslov, KI; Wang, LV
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
January 1, 2014

Currently, laser fluence calibration is typically required for quantitative measurement of particle concentration in photoacoustic microscopy. In this paper, we present another quantitative approach to measure absolute absorber concentrations by photoacoustic correlation spectroscopy. The proposed method is based on the fact that the Brownian motion induces particle count fluctuation in the detection volume. We first derived a theoretical model for photoacoustic signals and then applied our method to quantitative measurement of different concentrations of various particles. The experimental results agreed well with the predictions from the theoretical model, suggesting that our method can be used for absolute particle concentrations measurement. © 2014 SPIE.

Duke Scholars

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9780819498564

Publication Date

January 1, 2014

Volume

8943
 

Citation

APA
Chicago
ICMJE
MLA
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Zhou, Y., Yao, J., Maslov, K. I., & Wang, L. V. (2014). Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8943). https://doi.org/10.1117/12.2036635
Zhou, Y., J. Yao, K. I. Maslov, and L. V. Wang. “Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 8943, 2014. https://doi.org/10.1117/12.2036635.
Zhou Y, Yao J, Maslov KI, Wang LV. Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2014.
Zhou, Y., et al. “Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8943, 2014. Scopus, doi:10.1117/12.2036635.
Zhou Y, Yao J, Maslov KI, Wang LV. Photoacoustic correlation spectroscopy for calibration-free absolute quantification of particle concentration. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2014.

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9780819498564

Publication Date

January 1, 2014

Volume

8943