Photoacoustic microscopy with enhanced resolution and imaging depth aided by optical clearing

Published

Conference Paper

Both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (ORPAM) deteriorate sharply with depth due to strong light scattering in tissue. To reduce tissue scattering, we propose to use glycerol as an optical clearing agent in OR-PAM. Our results show that the imaging performance of OR-PAM can be greatly enhanced by optical clearing both in vitro and in vivo. © 2014 SPIE.

Full Text

Duke Authors

Cited Authors

  • Zhou, Y; Yao, J; Wang, LV

Published Date

  • January 1, 2014

Published In

Volume / Issue

  • 8943 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9780819498564

Digital Object Identifier (DOI)

  • 10.1117/12.2036636

Citation Source

  • Scopus