Ultrasound-heated photoacoustic flowmetry.
Journal Article
We report the development of photoacoustic flowmetry assisted by high-intensity focused ultrasound (HIFU). This novel method employs HIFU to generate a heating impulse in the flow medium, followed by photoacoustic monitoring of the thermal decay process. Photoacoustic flowmetry in a continuous medium remains a challenge in the optical diffusive regime. Here, both the HIFU heating and photoacoustic detection can focus at depths beyond the optical diffusion limit (~1 mm in soft tissue). This method can be applied to a continuous medium, i.e., a medium without discrete scatterers or absorbers resolvable by photoacoustic imaging. Flow speeds up to 41 mm·s-1 have been experimentally measured in a blood phantom covered by 1.5-mm-thick tissue.
Full Text
Duke Authors
Cited Authors
- Wang, L; Yao, J; Maslov, KI; Xing, W; Wang, LV
Published Date
- November 2013
Published In
Volume / Issue
- 18 / 11
Start / End Page
- 117003 -
PubMed ID
- 24194064
Pubmed Central ID
- 24194064
Electronic International Standard Serial Number (EISSN)
- 1560-2281
International Standard Serial Number (ISSN)
- 1083-3668
Digital Object Identifier (DOI)
- 10.1117/1.jbo.18.11.117003
Language
- eng