Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model
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, Conference
Hu, S; Oladipupo, S; Yao, J; Santeford, AC; Maslov, K; Kovalski, J; Arbeit, JM; Wang, LV
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
May 3, 2010
A major obstacle in studying angiogenesis is the inability to noninvasively image neovascular development in an individual animal. We applied optical-resolution photoacoustic microscopy (OR-PAM) to determine the kinetics of hypoxia-inducible factor-1 (HIF-1)-mediated angiogenesis in a transgenic mouse model. During continuous 30-day activation of HIF-1α, we used OR-PAM to monitor alterations in microvasculature in transgenic mice compared to nontransgenic mice. OR-PAM has demonstrated the potential to precisely monitor antiangiogenic therapy of human cancers, allowing for rapid determinations of therapeutic efficacy or resistance. © 2010 Copyright SPIE - The International Society for Optical Engineering.
Duke Scholars
Published In
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
DOI
ISSN
1605-7422
ISBN
9780819479600
Publication Date
May 3, 2010
Volume
7564
Citation
APA
Chicago
ICMJE
MLA
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Hu, S., Oladipupo, S., Yao, J., Santeford, A. C., Maslov, K., Kovalski, J., … Wang, L. V. (2010). Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7564). https://doi.org/10.1117/12.841177
Hu, S., S. Oladipupo, J. Yao, A. C. Santeford, K. Maslov, J. Kovalski, J. M. Arbeit, and L. V. Wang. “Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 7564, 2010. https://doi.org/10.1117/12.841177.
Hu S, Oladipupo S, Yao J, Santeford AC, Maslov K, Kovalski J, et al. Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2010.
Hu, S., et al. “Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7564, 2010. Scopus, doi:10.1117/12.841177.
Hu S, Oladipupo S, Yao J, Santeford AC, Maslov K, Kovalski J, Arbeit JM, Wang LV. Optical-resolution photoacoustic microscopy of angiogenesis in a transgenic mouse model. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2010.
Published In
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
DOI
ISSN
1605-7422
ISBN
9780819479600
Publication Date
May 3, 2010
Volume
7564