Gold-Catalyzed Intermolecular, anti-Markovnikov Hydroarylation of Methylenecyclopropanes with Indoles.

Journal Article (Journal Article)

Cationic gold complexes containing an N-heterocyclic carbene ligand catalyze the intermolecular anti-Markovnikov hydroarylation of monosubstituted and cis- and trans-disubstituted methylenecyclopropanes (MCPs) with N-alkyl and 1,2-dialkyl indoles to form the corresponding 3-(cyclopropylmethyl)indoles in high regio- and diastereoselectivity and in good to excellent chemical yield.

Full Text

Duke Authors

Cited Authors

  • Timmerman, JC; Schmitt, WW; Widenhoefer, RA

Published Date

  • October 2016

Published In

Volume / Issue

  • 18 / 19

Start / End Page

  • 4966 - 4969

PubMed ID

  • 27629585

Pubmed Central ID

  • 27629585

Electronic International Standard Serial Number (EISSN)

  • 1523-7052

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/acs.orglett.6b02431


  • eng