Gold-Catalyzed Intermolecular, anti-Markovnikov Hydroarylation of Methylenecyclopropanes with Indoles.
Journal Article
Cationic gold complexes containing an N-heterocyclic carbene ligand catalyze the intermolecular anti-Markovnikov hydroarylation of monosubstituted and cis- and trans-disubstituted methylenecyclopropanes (MCPs) with N-alkyl and 1,2-dialkyl indoles to form the corresponding 3-(cyclopropylmethyl)indoles in high regio- and diastereoselectivity and in good to excellent chemical yield.
Full Text
Duke Authors
Cited Authors
- Timmerman, JC; Schmitt, WW; Widenhoefer, RA
Published Date
- October 2016
Published In
Volume / Issue
- 18 / 19
Start / End Page
- 4966 - 4969
PubMed ID
- 27629585
Electronic International Standard Serial Number (EISSN)
- 1523-7052
International Standard Serial Number (ISSN)
- 1523-7060
Digital Object Identifier (DOI)
- 10.1021/acs.orglett.6b02431
Language
- eng