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Molecular neurobiology: Implications for insecticide action and resistance

Publication ,  Journal Article
Soderlund, DM; Bloomquist, JR; Wong, F; Payne, LL; Knipple, DC
Published in: Pesticide Science
January 1, 1989

Recent advances in molecular neurobiology have provided an unprecedented insight into the structure and function of the three principal target sites for neurotoxic insecticides: acetylcholinesterase, the 4‐aminobutyric acid (GABA) receptor–chloride ionophore complex, and the voltage‐sensitive sodium channel. This paper reviews some of these advances and their current or potential application to problems in insecticide resistance. It particularly emphasizes studies of the molecular biology of voltage‐dependent sodium channels in the context of resistance to DDT and pyrethroids resulting from reduced neuronal sensitivity. Copyright © 1989 John Wiley & Sons, Ltd

Duke Scholars

Published In

Pesticide Science

DOI

EISSN

1096-9063

ISSN

0031-613X

Publication Date

January 1, 1989

Volume

26

Issue

4

Start / End Page

359 / 374

Related Subject Headings

  • Entomology
  • 0703 Crop and Pasture Production
  • 0502 Environmental Science and Management
 

Citation

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Soderlund, D. M., Bloomquist, J. R., Wong, F., Payne, L. L., & Knipple, D. C. (1989). Molecular neurobiology: Implications for insecticide action and resistance. Pesticide Science, 26(4), 359–374. https://doi.org/10.1002/ps.2780260404
Soderlund, D. M., J. R. Bloomquist, F. Wong, L. L. Payne, and D. C. Knipple. “Molecular neurobiology: Implications for insecticide action and resistance.” Pesticide Science 26, no. 4 (January 1, 1989): 359–74. https://doi.org/10.1002/ps.2780260404.
Soderlund DM, Bloomquist JR, Wong F, Payne LL, Knipple DC. Molecular neurobiology: Implications for insecticide action and resistance. Pesticide Science. 1989 Jan 1;26(4):359–74.
Soderlund, D. M., et al. “Molecular neurobiology: Implications for insecticide action and resistance.” Pesticide Science, vol. 26, no. 4, Jan. 1989, pp. 359–74. Scopus, doi:10.1002/ps.2780260404.
Soderlund DM, Bloomquist JR, Wong F, Payne LL, Knipple DC. Molecular neurobiology: Implications for insecticide action and resistance. Pesticide Science. 1989 Jan 1;26(4):359–374.

Published In

Pesticide Science

DOI

EISSN

1096-9063

ISSN

0031-613X

Publication Date

January 1, 1989

Volume

26

Issue

4

Start / End Page

359 / 374

Related Subject Headings

  • Entomology
  • 0703 Crop and Pasture Production
  • 0502 Environmental Science and Management