[Localization of matrix-associated elements in the 5'-region of the rat estrogen sulfotransferase gene].

Published

Journal Article

Potential matrix-associated elements in the 5'-region of the rat estrogen sulfotransferase gene (Ste1) were searched for and characterized. The DNA fragments corresponding to the regions -800/+1048 and +1049/+2038 relative to the main point of transcription initiation were found to be bound to the nuclear matrix in vitro. A permanent association of the 5'-region of the Ste1 gene with the nuclear matrix in rat hepatocytes was found, the most probable site of attachment being the region -352/-152. No differences were found in the attachment of the 5'-region of the Ste1 gene to the nuclear matrix in the liver of males where the gene is actively transcribed and in that of females where it is inactive.

Full Text

Duke Authors

Cited Authors

  • Morozov, IA; Astapova, II; Smirnov, AN; Rubtsov, PM

Published Date

  • July 1, 2004

Published In

Volume / Issue

  • 30 / 4

Start / End Page

  • 389 - 393

PubMed ID

  • 15469013

Pubmed Central ID

  • 15469013

International Standard Serial Number (ISSN)

  • 0132-3423

Language

  • rus

Conference Location

  • Russia (Federation)