Asymmetric division: An antitumor player?
Publication
, Journal Article
Wang, L; Bu, P; Shen, X
Published in: Mol Cell Oncol
July 2016
miR-34a-mediated asymmetric cell division reins in excessive stem cell expansion during tissue regeneration in the intestine and colon. Loss of miR-34a switches asymmetric division to symmetric division and enhances stem cell proliferation. Asymmetric division also occurs in the early stages of colon cancer stem cells. Mechanistically, miR-34a, Numb, and Notch form a feed-forward loop that specifies cell fate when stem cells divide.
Duke Scholars
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
July 2016
Volume
3
Issue
4
Start / End Page
e1164279
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics
Citation
APA
Chicago
ICMJE
MLA
NLM
Wang, L., Bu, P., & Shen, X. (2016). Asymmetric division: An antitumor player? Mol Cell Oncol, 3(4), e1164279. https://doi.org/10.1080/23723556.2016.1164279
Wang, Lihua, Pengcheng Bu, and Xiling Shen. “Asymmetric division: An antitumor player?” Mol Cell Oncol 3, no. 4 (July 2016): e1164279. https://doi.org/10.1080/23723556.2016.1164279.
Wang L, Bu P, Shen X. Asymmetric division: An antitumor player? Mol Cell Oncol. 2016 Jul;3(4):e1164279.
Wang, Lihua, et al. “Asymmetric division: An antitumor player?” Mol Cell Oncol, vol. 3, no. 4, July 2016, p. e1164279. Pubmed, doi:10.1080/23723556.2016.1164279.
Wang L, Bu P, Shen X. Asymmetric division: An antitumor player? Mol Cell Oncol. 2016 Jul;3(4):e1164279.
Published In
Mol Cell Oncol
DOI
ISSN
2372-3556
Publication Date
July 2016
Volume
3
Issue
4
Start / End Page
e1164279
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3205 Medical biochemistry and metabolomics