Particle streak velocimetry-optical coherence tomography: a novel method for multidimensional imaging of microscale fluid flows.


Journal Article

We present a new OCT method for flow speed quantification and directional velocimetry: particle streak velocimetry-OCT (PSV-OCT). PSV-OCT generates two-dimensional, 2.5-vector component (vx ,|vy |,vz ) maps of microscale flow velocity fields. Knowledge of 2.5-vector components also enables the estimation of total flow speed. The enabling insight behind PSV-OCT is that tracer particles in sparsely-seeded fluid flow trace out streaks in (x,z,t)-space. The streak orientations in x-t and z-t yield vx and vz , respectively. The in-plane (x-z plane) residence time yields the out-of-plane speed |vy |. Vector component values are generated by fitting streaks to a model of image formation that incorporates equations of motion in 3D space. We demonstrate cross-sectional estimation of (vx ,|vy |,vz ) in two important animal models in ciliary biology: Xenopus embryos (tadpoles) and mouse trachea.

Full Text

Duke Authors

Cited Authors

  • Zhou, KC; Huang, BK; Gamm, UA; Bhandari, V; Khokha, MK; Choma, MA

Published Date

  • April 2016

Published In

Volume / Issue

  • 7 / 4

Start / End Page

  • 1590 - 1603

PubMed ID

  • 27375926

Pubmed Central ID

  • 27375926

Electronic International Standard Serial Number (EISSN)

  • 2156-7085

International Standard Serial Number (ISSN)

  • 2156-7085

Digital Object Identifier (DOI)

  • 10.1364/BOE.7.001590


  • eng