Sector laser photocoagulation for the prevention of macular edema after plaque radiotherapy for uveal melanoma: a pilot study.
Journal Article (Journal Article)
OBJECTIVE: To investigate the role of sector laser photocoagulation for prevention of macular edema after plaque radiotherapy for uveal melanoma. METHODS: Noncomparative, pilot interventional case series. The main outcome measure was optical coherence tomography-evident macular edema. RESULTS: A total of 29 patients had sector laser photocoagulation (sector panretinal photocoagulation) and sub-Tenon triamcinolone injection. The median tumor thickness and base was 3.3 mm and 10.0 mm. The median radiation dose and rate to the macula was 2,944 cGy and 31.0 cGy/hour. At the 12-month and 24-months follow-up, cystoid macular edema was found in 17% and 24% of the sector panretinal photocoagulation group. There were no major side effects registered. CONCLUSION: Sector panretinal photocoagulation in combination with sub-Tenon triamcinolone appears to show potential as a safe and beneficial intervention for the prevention of macular edema after plaque radiotherapy for uveal melanoma in this series.
Full Text
Duke Authors
Cited Authors
- Materin, MA; Bianciotto, CG; Wu, C; Shields, CL
Published Date
- September 2012
Published In
Volume / Issue
- 32 / 8
Start / End Page
- 1601 - 1607
PubMed ID
- 22466484
Electronic International Standard Serial Number (EISSN)
- 1539-2864
Digital Object Identifier (DOI)
- 10.1097/IAE.0b013e3182437e70
Language
- eng
Conference Location
- United States