Improving the tools of clinical pharmacology: Goals for 2017 and beyond.

Journal Article (Journal Article)

Current trends in pronounced late-stage attrition rates of promising drug candidates are a pressing concern for patients, providers, and other stakeholders across the health care system. Here, we describe six areas in which clinical pharmacology methods and frameworks can help ameliorate these trends in late-stage attrition and increase the efficiency of drug development and evaluation. These recommendations are based, in part, on previous stakeholder engagement and input, as well as a previously published white paper.

Full Text

Duke Authors

Cited Authors

  • Zineh, I; Abernethy, D; Hop, C; Bello, A; McClellan, MB; Daniel, GW; Romine, MH

Published Date

  • January 2017

Published In

Volume / Issue

  • 101 / 1

Start / End Page

  • 22 - 24

PubMed ID

  • 27727433

Electronic International Standard Serial Number (EISSN)

  • 1532-6535

International Standard Serial Number (ISSN)

  • 0009-9236

Digital Object Identifier (DOI)

  • 10.1002/cpt.530


  • eng