L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine.
Publication
, Journal Article
Tourian, A; Callahan, M; Hung, W
Published in: Neurochem Res
December 1983
L-Glutamine D-Fructose-6-P aminotransferase regulates hexosamine synthesis. An affinity purified human fibroblast aminotransferase and specific radioisotope assays developed by us were used to show an independent inhibition of the aminotransferase by Glucose-6-P. More interestingly, at concentration of UDP-N-Acetylglucosamine and glucose-6-P where either sugar has no independent inhibitory effect, there is an allosteric and significant inhibition of the aminotransferase.
Duke Scholars
Published In
Neurochem Res
DOI
ISSN
0364-3190
Publication Date
December 1983
Volume
8
Issue
12
Start / End Page
1589 / 1595
Location
United States
Related Subject Headings
- Uridine Diphosphate Sugars
- Uridine Diphosphate N-Acetylglucosamine
- Neurology & Neurosurgery
- Humans
- Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
- Glucosephosphates
- Glucose-6-Phosphate
- Fibroblasts
- Drug Synergism
- Dose-Response Relationship, Drug
Citation
APA
Chicago
ICMJE
MLA
NLM
Tourian, A., Callahan, M., & Hung, W. (1983). L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine. Neurochem Res, 8(12), 1589–1595. https://doi.org/10.1007/BF00964160
Tourian, A., M. Callahan, and W. Hung. “L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine.” Neurochem Res 8, no. 12 (December 1983): 1589–95. https://doi.org/10.1007/BF00964160.
Tourian A, Callahan M, Hung W. L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine. Neurochem Res. 1983 Dec;8(12):1589–95.
Tourian, A., et al. “L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine.” Neurochem Res, vol. 8, no. 12, Dec. 1983, pp. 1589–95. Pubmed, doi:10.1007/BF00964160.
Tourian A, Callahan M, Hung W. L-glutamine D-fructose-6-P aminotransferase regulation by glucose-6-P and UDP-N-acetylglucosamine. Neurochem Res. 1983 Dec;8(12):1589–1595.
Published In
Neurochem Res
DOI
ISSN
0364-3190
Publication Date
December 1983
Volume
8
Issue
12
Start / End Page
1589 / 1595
Location
United States
Related Subject Headings
- Uridine Diphosphate Sugars
- Uridine Diphosphate N-Acetylglucosamine
- Neurology & Neurosurgery
- Humans
- Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
- Glucosephosphates
- Glucose-6-Phosphate
- Fibroblasts
- Drug Synergism
- Dose-Response Relationship, Drug