Incorporating privileged genetic information for fundus image based glaucoma detection.

Journal Article (Journal Article)

Visual features extracted from retinal fundus images have been increasingly used for glaucoma detection, as those images are generally easy to acquire. In recent years, genetic researchers have found that some single nucleic polymorphisms (SNPs) play important roles in the manifestation of glaucoma and also show superiority over fundus images for glaucoma detection. In this work, we propose to use the SNPs to form the so-called privileged information and deal with a practical problem where both fundus images and privileged genetic information exist for the training subjects, while the test objects only have fundus images. To solve this problem, we present an effective approach based on the learning using privileged information (LUPI) paradigm to train a predictive model for the image visual features. Extensive experiments demonstrate the usefulness of our approach in incorporating genetic information for fundus image based glaucoma detection.

Full Text

Duke Authors

Cited Authors

  • Duan, L; Xu, Y; Li, W; Chen, L; Wing, DWK; Wong, TY; Liu, J

Published Date

  • 2014

Published In

  • Med Image Comput Comput Assist Interv

Volume / Issue

  • 17 / Pt 2

Start / End Page

  • 204 - 211

PubMed ID

  • 25485380

Digital Object Identifier (DOI)

  • 10.1007/978-3-319-10470-6_26


  • eng

Conference Location

  • Germany